Inavolisib (Itovebi) is a new targeted therapy for HR+ HER2-negative metastatic breast cancer with a PIK3CA mutation.

Estrogen and progesterone combined in OCs act in a ... thereby inhibiting ovulation. Gonadotropin inhibition also has the effect of reducing the androgen production of ovarian theca cells and ...

MR = Mineralocorticoid receptor; PR = Progesterone receptor. The relative binding affinity (%) of the main progestins discussed in this paper for the different steroid receptors is indicated.

Men lose more weight than women on a ketogenic diet, according to a comprehensive review in Frontiers in Nutrition. Sex ...

The FDA has cleared the IL-36 receptor inhibitor under the Spevigo brand name to treat the devastating eruptions of painful blisters, known as flares, that are a characteristic of GPP. The flares ...