Findings from the new study were published recently in Cancer Research through an article titled, “Structural Optimization and Enhanced Prodrug-Mediated Delivery Overcomes Camptothecin ...

Utilizing this prodrug strategy, we have synthesized the novel prodrug TTFA-Platin, which combines two powerful drugs: TTFA (which targets mitochondria, which is the powerhouse of the cell) with ...

To make this prodrug strategy biocompatible, Tanaka and co-workers shielded the gold catalyst from glutathione by encasing the catalyst within the protein human serum albumin. “The gold artificial ...

Jarkko Rautio of the School of Pharmacy at University of Eastern Finland demonstrates the versatility of prodrugs strategies in medicinal chemistry to overcome various ADMET barriers (absorption, ...

Citation: Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed (2022, November 16) retrieved 24 May 2025 from https://medicalxpress ...

POSTECH professor Won Jong Kim’s research team develops self-immolative nitric oxide anti-cancer prodrug. The drug removes cancer cells in lymph nodes after being conjugated to proteins.

(Medical Xpress)—Researchers at the University of Georgia have developed a new prodrug that promises to reduce many of the negative side effects caused by cisplatin, a commonly prescribed ...

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed Augmented drug eliminates cancer cells without causing toxicity ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how branched glycopolymer prodrug-derived nanoassembly combined with a STING agonist activates an immuno-supportive status ...

Askgene Pharma Inc. has received FDA clearance of its IND application to start a phase I study of ASKG-915, a novel and proprietary anti-PD-1/IL-15 prodrug fusion molecule for the treatment of cancer.