One-Pot Biocatalytic Synthesis of Primary, Secondary, and Tertiary Amines with Two Stereocenters from α,β-Unsaturated Ketones Using Alkyl-Ammonium Formate. ACS Catalysis , 2022; 14459 DOI: 10. ...

Primary amines, in which a nitrogen atom is bonded to just one carbon, are often made by reducing nitrile groups using hydrogen. ... and then coupling the imine to a primary or secondary amine.

The team combined readily available terminal olefins, secondary amines, an oxidant, and a palladium sulfoxide catalyst to make over 80 tertiary amines, including drugs and drug derivatives ...

The production of primary amines is so difficult because these products are very reactive and can thus continue to react to form secondary and tertiary amines as undesired byproducts.

All the latest science news on amines from Phys.org. Find the latest news, advancements, and breakthroughs. ... Enzymatic synthesis of primary, secondary and tertiary amines containing two ...

Amines are often categorised as primary, secondary and tertiary on the basis of the number of hydrogen atoms replaced by alkyl. When one hydrogen atom of ammonia is replaced by R or Ar, you get a ...

Article Title. ne-Pot Biocatalytic Synthesis of Primary, Secondary, and Tertiary Amines with Two Stereocenters from α,β-Unsaturated Ketones Using Alkyl-Ammonium Formate ...