Presynaptic NMDA receptors can shape timing-dependent long-term depression in a way that departs from their classic postsynaptic role.

However, whether and how presynaptic adhesion molecules trans-synaptically regulate the localization and stabilization of postsynaptic neurotransmitter receptors remained largely unclear.

In other words, the signal that is carried from the first nerve fiber (presynaptic neuron) to the next (postsynaptic neuron) is transmitted by an electrical signal or a chemical one. Once a signal ...

Interaction with the external world results in synaptic activity, and patterns in this activity, both presynaptic and postsynaptic, can lead to changes in the connections between individual ...

At synapses, signals are sent by presynaptic neurons and received by postsynaptic neurons. At most synapses, communication occurs via chemical messengers—or neurotransmitters. When an electrical ...

Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent continuous stimulation of postsynaptic ... reabsorbed back into the presynaptic neuron and ...

"Given the presynaptic role of synucleins in regulating ... "Consistent with this hypothesis, postsynaptic expression of tetanus toxin light chain, which cleaves synaptobrevin SNAREs, also blocks ...

Each of these levels covers a different scenario that can occur between the presynaptic and postsynaptic cell, such as spatial summation or coincidence potentiation. Using their knowledge of these ...

1 The oft-studied molecular players in learning and memory, including calcium influx, the NMDA receptor, and protein kinases, are postsynaptic, whereas RIM1 is presynaptic. The deficits observed in ...

The endocannabinoids do not follow the path of a typical chemical synaptic signaling which is for a neurotransmitter to flow from a presynaptic neuron to a postsynaptic neuron and attach to a specific ...