Recalcitrant infections are often caused by dormant bacteria, including persisters and viable but nonculturable cells. Here, the authors explore how composition and structure of protein ...

Biochemical and physiological mechanisms of adaptation of organisms to the marine environment. Special emphasis is on biological responses to temperature, salinity, carbon dioxide, pH and bicarbonate ...

008). Topline data were announced from a phase 3 trial evaluating Brimochol TM preservative-free (PF), an investigational pupil-modulating therapeutic, in adults with presbyopia. Study ...

Tenpoint plans to submit an FDA new drug application in the first half of 2025. Patients with presbyopia experienced improvements in near vision after treatment with Brimochol PF in a second phase ...

In a phase 3 trial, Tenpoint Therapeutics’ eye drop—a combination of carbachol and brimonidine—improved vision for patients with presbyopia for up to eight hours. The top-line results come f ...

Further details will be presented at upcoming scientific meetings. “Tenpoint Therapeutics is the only company in the presbyopia category to demonstrate contribution of elements with BRIMOCHOL™ PF, ...

The merger brings together a late-stage, potentially best-in-class, presbyopia-correcting eye drop, BRIMOCHOL™ PF, on track for NDA filing in 1H, 2025, with a promising pipeline of innovative ...