Specifically, a recent deep mutational scanning study of the tetracycline repressor (TetR) revealed an unexpectedly broad distribution of allostery hotspots throughout the protein structure. Using ...

MC Gambetta, J Müller, O-GlcNAcylation prevents aggregation of the polycomb group repressor polyhomeotic. Dev Cell 31, 629–639 (2014). Crossref. PubMed. Google Scholar. 15. JJP Maury, et al., RING1B O ...

Magnetic studies indicate that complex 1 exhibits two slow magnetic relaxation processes with effective energy barrier U eff = 55.71 K under a zero direct-current field, which is attributed to the two ...

However, CLOCK is phosphorylated by CK1δ in a PER/CRY-dependent manner, a modification required for displacement of the BMAL1/CLOCK complex from DNA (Cao et al, 2021). This implies that the repressor ...

Similarly, only Nedd4-1, Nedd4-2, and WWP1 promote the in vitro ubiquitination and degradation of Robo1, despite the fact that other E3 ligases such as Smurf can form a ternary complex with Robo1 and ...