However, the role of tumour-infiltrating B cells (TIBs) remains controversial. Here, we investigate the impact of TIBs and their interaction with T cells on HCC patient prognosis. Design Tissue ...

Follicular Dendritic Cell (FDC) Sarcoma: HV-CD often shows FDC proliferation, which can evolve into FDC sarcoma. ・ Plasma Cell Neoplasms: These can appear similar to PC-CD, especially when monotypic ...

Plasma Cell Neoplasms: These can appear similar to PC-CD, especially when monotypic plasma cell populations are present. ・ IgG4-related Disease (IgG4-RD): Frequently overlaps with PC-CD and iMCD ...

A Harvard study published in the journal Nature (2021) has revealed that chronic stress disrupts hair follicle stem cells ... ranging from platelet-rich plasma (PRP) injections to serums infused ...

Activation-induced cytidine deaminase (AID) serves as a critical molecular orchestrator in the germinal center (GC) reaction within secondary lymphoid organs (SLOs), driving the production of ...

The differential diagnosis for IgG4-RD includes conditions such as autoimmune pancreatitis, eosinophilic syndromes, multicentric Castleman disease, and plasma cell neoplasm, among others. Valencia OG, ...

In addition to BCMA-directed therapies, other CAR T targets such as GPRC5D and CD229 also appear promising for plasma cell dyscrasias. CD229-directed CAR T was investigated in MM and included 3 PCL ...

Neoplastic cell morphology in peripheral blood (A) and bone marrow aspirate films (B) showing small- to medium-sized lymphoplasmacytic lymphocytes (May Grunwald Giemsa stain, 1000×). Bone marrow ...

BPDCN is an aggressive type of blood cancer that originates from plasmacytoid dendritic cells (pDCs), a component of the immune system that produces type 1 interferon cytokines. These cytokines ...

RNA-sequencing analyses identified EBV oncoprotein effects on GC B-cell target genes, including up-regulation of multiple proinflammatory chemokines and master regulators of plasma cell ...