Lysosomes are subcellular organelles that are mainly responsible for degradation of proteins internalized by cells by endocytosis and phagocytosis. Upon uptake, proteins and soluble components ...

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Lysosomes are dynamic organelles critical for cellular degradation and signaling, safeguarded by a limiting membrane that prevents leakage of harmful contents into the cytoplasm. Upon lysosomal damage ...

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Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say. Holly Barker is a freelance journalist ...