Proteases are enzymes that catalyse hydrolysis of the peptide and isopeptide bonds that join amino acids ... mediates holoenzyme formation and disrupts Clp system regulation.

These findings demonstrate the crucial role of δ-COP in APP metabolism and, consequently, the generation of amyloid-β (Aβ) peptide, providing previously nondescribed mechanistic ... a possible model ...

It also helps that Jay can share this bond with Ted now, too, and, eventually, his two younger siblings. Tagseth’s interest in Pokémon reignited similarly, when he was recovering from a back ...

Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana─Champaign, Urbana, Illinois 61801, United States Department of Materials Science and Engineering, University of ...

Institute of Quantitative Biology, Biochemistry and Biotechnology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FF, U.K. Institute of Quantitative Biology, Biochemistry and ...

Lariocidin, a lasso-shaped peptide with ... inhibits protein synthesis by interfering with translocation but also induces translation errors (miscoding), giving it a dual mechanism of action.

Peptide-based self-assembled monolayers (peptide-SAMs ... Therefore, biomolecules are endowed with the capability of forming specific bonds with their target molecules and of rejecting other ...

The obtained results allow us to reveal the detailed mechanism of inhibition of bacterial translation by Ami ... Amicoumacin A Does Not Interfere With Decoding and Peptide Bond Formation Ami slows ...

These macrocyclization reactions use the substrates amino terminus instead of water to deacylate, so a peptide bond is formed. How solvent-exposed plant AEPs macrocyclize is poorly understood. Here we ...

The overall objective of this Brief Review is 2-fold: first, to highlight the vasodilatory actions of relaxin, particularly in the context of pregnancy; and, second, to outline current understanding ...