Using western blot analysis and ChIP-qPCR, we show that Eed-/- ESCs lack EED protein in total lysates or bound to chromatin (Fig. 4a and Supplementary Fig. 8c,d) have reduced protein levels of ...

What is western blotting? In 1975, Southern invented a new method that enabled analysis of DNA identity, size and abundance. It involved the use of electrophoresis to separate DNA fragments based on ...

If it’s mutated, cells can grow uncontrollably, and cancer can arise—a fact that has made PRC2 a source of keen interest for drug developers. New research by scientists at CU Boulder and Harvard ...

A classic laboratory technique, western blotting, has been used by researchers for decades, and it is nearly obsolete. “Biologists currently are stuck in a time warp—they basically use the ...

Find out more about how commercial antibody providers are sharing the responsibility for antibody validation, with Bethyl Laboratories’ solution for a practical, high-throughput method for validating ...