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BCAT2 调控前列腺癌关键通路:开辟诊疗新方向
前列腺癌严重威胁男性健康,现有治疗手段存在局限。研究人员聚焦分支链氨基酸(BCAAs)及 BCAT2 在前列腺癌中的作用。发现 BCAT2 高表达与预后不良相关,其通过与 PCBP1 互作调节 PI3K/AKT 通路,影响细胞进程。该研究为前列腺癌诊疗提供新靶点和思路。
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