Department of Radiation Oncology, Radboud University Nijmegen Medical Centre, Netherlands Activation of the phosphatidylinositol-3-kinase (PI3-K)/protein kinase B (AKT) pathway is associated with ...

Department of Radiation Oncology, Radboud University Nijmegen Medical Centre, Netherlands Activation of the phosphatidylinositol-3-kinase (PI3-K)/protein kinase B (AKT) pathway is associated with ...

38 Nevertheless, studies using proteomic analysis have confirmed AKT phosphorylation in FL samples, which is indicative of PI3K pathway activation. 39,40,42,43 Additional evidence for the ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

You will be redirected to our submission process. The phosphatidylinositol 3-kinase (PI3K)/mTOR pathway integrates signals from growth factors with nutrient signals and other conditions and controls ...

The goal of my laboratory is to understand the regulatory relationship between cellular signaling pathways and metabolic pathways. We are particularly interested in the PI3K (phosphoinositide-3-kinase ...

Emerging evidence suggests a role for PI3K/mTOR signalling in the pathology of organ fibrosis. The aim of this study was to delineate PI3K/mTOR signalling in response to TGF-β 1 stimulation of primary ...

These findings highlighted the potential applications of cordycepin as an anticancer agent, especially for cancer types that were reliant on PI3K/AKT/mTOR and similar protein kinase pathways for ...