资讯

Nature10 年
Glucose metabolism is inhibited by caspases upon the induction of apoptosis
Glycolysis is tightly regulated by the three allosteric enzymes, hexokinase (HK), phosphofructokinase-1 (PFK) and pyruvate kinase (PK), which catalyze the irreversible steps. HK, the first enzyme ...
EurekAlert!5 年
How cancer cells stiff-arm normal environmental cues to consume energy
They knew from their experiments that PFK, the limiting enzyme for glycolysis, is somehow removed after it's made if cells are grown on softer tissues. That finding caused the researchers to look ...
News Medical5 年
Researchers uncover how cancer cells override environmental cues to consume energy
They knew from their experiments that PFK, the limiting enzyme for glycolysis, is somehow removed after it's made if cells are grown on softer tissues. That finding caused the researchers to look ...
An energy trap for tumor cells: Researchers find enzyme blockade halts liver cancer growth
However, when the researchers blocked an earlier step in glycolysis, the enzyme glucose-6-phosphate isomerase, this had no ...