Researchers have uncovered how the breakdown of glycogen may protect the brain from neurodegeneration and Alzheimer's.

Research uncovered how glycogen metabolism in neurons impacts neurodegenerative diseases like Alzheimer's. Disruption in this ...

A new study from scientists at the Buck Institute for Research on Aging has revealed a surprising player in the battle ...

A new study from scientists at the Buck Institute for Research on Aging has revealed a surprising player in the battle ...

Scientists have uncovered a surprising sugar-related mechanism inside brain cells that could transform how we fight Alzheimer ...

Oxidative Stress: A state in which the production of reactive oxygen species exceeds the body’s antioxidant defences, potentially leading to cell damage. Glucose-6-Phosphate Dehydrogenase ...

Here, we demonstrate that Tyr‐Asp inhibits the enzymatic activity of GAPC. Tyr‐Asp feeding induced a shift of glucose 6‐phosphate (G6P) utilization from glycolysis to the pentose phosphate pathway ...

Erythritol may impair cellular functions essential to maintaining brain blood vessel health, according to researchers at the ...

*仅供医学专业人士阅读参考包括阿尔茨海默病（AD）和含tau包涵体的额颞叶变性（FTLD-tau）在内，以微管相关蛋白tau异常聚集为特征的一组神经退行性疾病被合称为tau蛋白病。在对tau蛋白病机制的探索中，近年来的研究显示，神经元中糖原代谢异常与 ...

来自以色列巴伊兰大学的研究团队发现，神经元糖原代谢通过磷酸戊糖途径 (PPP)维持氧化还原稳态，在果蝇模型和FTLD-tau患者iPSC来源神经元中证实其可缓解tau蛋白病变相关氧化应激。该研究揭示了饮食限制 (DR)通过促进糖原分解发挥神经保护作用，为阿尔茨海默病 (AD)等tau蛋白病变提供了新治疗靶点。

A popular sugar substitute can impair cellular functions vital for brain blood vessel health, new evidence has demonstrated.