This step proceeds through a nucleophilic addition-elimination mechanism involving an attack of the dimethylamine on dicyanodiamide, followed by cyclization and rearrangement. Subsequently, the ...

In the IGNR system, reline consisting of choline chloride and urea acted as both a solvent and a nucleophile generator, and the nucleophilic addition–elimination mechanism was verified by model ...

The structure provides key insights into the mechanism of catalysis and ... including the product of thia-Michael addition of glutathione to a Dhb-containing peptide that represents the activation ...

The important reaction channels are those corresponding to bimolecular nucleophilic substitution (SN2) and to bimolecular elimination (E2): their relative role has been assessed and alternative ...

Textbooks describe it as a stepwise addition–elimination sequence with a negatively charged intermediate ... and the paper provides what looks like a fairly easy way to study them – it goes beyond ...

In this short paper, a detailed investigation is made of one of the leading suggestions for O–O bond formation in photosystem II. The mechanism studied is a nucleophilic attack by a water molecule on ...