"Neural tube defects can be caused by variants in over 300 genes in the mouse, so we anticipate that many genes also are likely to be involved in the human condition." ...

Cyborg tadpoles could provide new insights into brain development and help to understand diseases that manifest in early ...

A developing mouse neural tube. Hedgehog signalling is required to produce different types of neuronal progenitor cells, indicated by the different colours. THC inhibits Hedgehog signalling in ...

The National Institute of Health (NIH) announced on Aug. 25, 2022, that scientists funded in part by the NIH have successfully generated a mouse embryo model, or embryoid, that develops beyond the ...

At first glance, the 10-days-old mouse embryo looked like any other. A closer look into the microscope, though, told Terry Hrubec something was wrong. The embryo’s neural tube—what would ...

Furthermore, many pNSCs that migrate out of the neural tube can differentiate into mature ... from neuroepithelium exist outside the mouse central nervous system, Nature Cell Biology (2025).

to investigate the genetic landscape of neural tube defects (NTDs). NTDs are the most common birth defect of the central nervous system and some of the most devastating congenital conditions.

It helps to form the RNA and DNA that tell our cells what to do. Neural tube birth defects occur in an unborn baby's brain or spine. The neural tube forms in the embryo and later becomes the baby ...