But for many, it's all a mystery. How does it all actually work? Creating images using AI and a text prompt was the first mainstream AI application to astonish the world way back in 2022.

Tumor cell deaths can benefit tumors. A paradox? Not at all. If, for example, a dying tumor cell undergoes necroptosis, it can release inflammatory factors that can enhance or diminish antitumor ...

Necroptosis is critical for regulating intestinal epithelial cells (IECs). Butyric acid (BA), produced during intestinal microbial metabolism, protects the intestinal epithelial barrier.

Necroptosis, a programmed cell death mechanism distinct from apoptosis, has garnered attention for its role in various pathological conditions. While initially recognized for its involvement in cell ...

Necroptosis is a form of programmed cell death, distinguished by rupturing of the cell membrane, swelling of the organelles, and spillage of internal cellular components. This form of cell death ...

Oxidative stress can trigger a type of programmed cell death called necroptosis. According to a new study, the environmental pollutant arsenite can induce necroptosis, but the process requires the ...

Figure 2 Necroptosis: a regulatory cell death. The death receptor signaling pathway is responsible for necroptosis This image depicts the interaction between tumor necrosis factor (TNF) and TNF ...

Necroptosis is the best-described form of programmed necrosis triggered by Death Receptors, Toll-Like Receptors and interferons and dependent on Receptor Interacting Protein Kinase 3 (RIPK3) and its ...

Polymyositis (PM) is a chronic inflammatory myopathy wherein muscle weakness is the most common symptom, leading to progressive and persistent disability. Its pathophysiology is assumingly the ...

Mixed lineage kinase domain‐like (MLKL) is the executioner in the caspase‐independent form of programmed cell death called necroptosis. Receptor‐interacting serine/threonine protein kinase 3 (RIPK3) ...

Here, we show that lipofuscin forms aggregates in lysosomes, which trigger lysosomal membrane permeabilization and subsequent atypical necroptosis. We provide evidence that necrosulfonamide, ...