Although NR4A (the nuclear receptor subfamily 4 group A) plays an important role in cardiovascular pathophysiology, the expression profile and biological function of NR4A member 1 (NR4A1) in platelets ...

为探究高血压性心脏病（HTN-HD）进展机制，研究人员发现心脏 - 脑 - 脾轴可调节心脏重塑，对防治心衰意义重大。 高血压性心脏病研究新突破：心脏 - 脑 - 脾轴的关键作用 在心血管疾病的庞大版图中，高血压性心脏病（Hypertensive heart disease，HTN-HD）犹如一颗 ...

安徽中医药大学附属六安医院（Department of Medical Oncology, Lu’an Hospital Affiliated To Anhui University of Chinese Medicine）的研究人员 Wanhui Dong 等人，在《Scientific Reports》期刊上发表了题为 “To investigate the tumor promotion ...

Innate T cells, including CD1d-restricted invariant natural killer T (iNKT) cells, are characterized by their rapid activation in response to non-peptide antigens, such as lipids. While the ...

DNA hypermethylation has been widely observed in temporal lobe epilepsy (TLE), in which NR4A1 knockdown has been reported to be able to alleviate seizure severity in mouse model, while the underlying ...

Within this study, we demonstrate that TLR4 stimulation using the endotoxin lipopolysaccharide (LPS) rapidly enhances NR4A1–3 expression in human and murine, primary and immortalized myeloid cells ...

Antibodies are proteins that recognize and bind to specific molecules, and so help the immune system to defend the body against foreign substances that are potentially harmful. In some cases, harmless ...