Patients with blood cancers like polycythemia vera, a kind of myeloproliferative neoplasm, may benefit in learning more about ...

Both small animal models and microphysiological systems gain in sophistication and value as they expedite in vivo preclinical testing.

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

Sanofi and Dren Bio, Inc., a private clinical-stage biopharmaceutical company, have entered into a definitive agreement under which Sanofi has agreed to acquire DR-0201, a targeted bispecific myeloid ...

were injected with anti-CD3 antibody (OKT3), anti-CD3/CD19 bispecific T-cell engager Blinatumomab, or VISTA-targeting antibody. Human myeloid and dendritic cells’ contribution was investigated in ...

1Department of Surgery, School of Clinical Medicine, HKU-SZH & LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

Dendritic cells (DC) are a type of antigen-presenting ... and response to inflammation or infection. The myeloid DCs differentiate from monocytes and macrophages in the presence of cytokines ...

Scientists have discover that 'elite controllers' have myeloid dendritic cells that display characteristics of trained innate immune cells. Immunity often calls to mind the adaptive immune ...

Thus, ablation of A20 in CD11c + myeloid cells contributes to attenuated renal blood flow, sodium transporter activation, and volume expansion, which could promote blood pressure elevation. Figure 8.

From the Division of Nephrology, Department of Medicine, Duke University and Durham VA Medical Centers, NC (X.L., N.P.R., Y.W., J.R., R.G., J.R.P., B.Y., M.A.S., S.D ...

The iPS cells were treated with a cocktail of growth factors and cytokines to generate definitive mesoderm and subsequently myeloid dendritic cells (mDC), utilizing feeder-free, chemically defined ...