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ACh is produced by the enzyme choline acetyltransferase and its actions are mediated through two types of acetylcholine receptors (AChRs) — the G protein-coupled muscarinic AChRs and the ...

The Research Center for Computer-Aided Drug Discovery, The Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China University of Chinese Academy of Sciences, ...

The aim of this editorial is to provide a background to this Frontiers Research Topic entitled “Insights in Clinical ... patients with type 2 diabetes, lupus nephritis, muscarinic orthosteric agonists ...

G protein coupled receptors (GPCRs) constitute the largest class of cell surface receptors. GPCR genes account for 5% of the human genome (1, 2). Of these receptors, all are seven membrane spanning ...