The CeraVe story began in 2005 after experts noticed that many skin conditions such as acne, eczema, psoriasis, and dry skin ...

For bodybuilders and fitness enthusiasts, changing body composition often reflects hard work and discipline—but knowing body composition is useful for anyone, and for more than just bragging rights.

Recent studies showed an unexpected complexity of extracellular vesicle (EV) biogenesis pathways. We previously found evidence that human colorectal cancer cells in vivo release large multivesicular ...

Here, we identified that phosphatidylinositol-3-phosphate (PI3P) mediates Arc capsid assembly and secretion through the endosomal–multivesicular body (MVB) pathway. Indeed, reconstituted Arc protein ...

Impaired protein degradation, especially endo-lysosome-mediated degradation of membrane proteins, is associated with cardiac hypertrophy progression. CHMP4C (charged multivesicular body protein 4C), a ...

MVB, multivesicular body; PVC, prevacuolar compartment; ER, endoplasmic reticulum; TGN, trans-Golgi network. In this mini review, we summarize the recent advances in research into the MVB and ...

Multivesicular bodies (MVBs) are specialized endosomes that contain intraluminal vesicles generated from invagination and budding of the limiting membrane. In the endocytic pathway, MVBs are late ...

A remarkable feature of NGF signaling is that, in order to elicit trophic actions on developing sensory and sympathetic neurons, the NGF/TrkA signal must be propagated retrogradely, from distal axons ...