Mitochondrial degeneration was suppressed by lifespan-extending nutritional interventions and by eight longevity mutations, which are all known to reduce cytosolic protein synthesis.

Researchers have discovered that the most aggressive melanomas, the deadliest form of skin cancer, overactivate two key ...

A deficiency in mitochondrial protein synthesis, due to the knockout of the MTO1 gene in hematopoietic cells, disrupts intracellular iron distribution, leading to fetal anemia.

In this study, a mouse model with a knockout of the mitochondrial tRNA modification enzyme (Mto1) exhibited defective mitochondrial protein synthesis, revealing a previously unknown molecular ...

RNA modification is responsible for the disruption of mitochondrial protein synthesis in Alzheimer's disease. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2024 / 04 ...

New work published in EMBO Reports has indicated that there are ribosomes, another kind of organelle that works to manufacture proteins, attached to mitochondria. Because of the role of ribosomes in ...

Mitochondrial pathways help melanoma cells become aggressive, and some currently available drugs target these pathways.Researchers have discovered ...

A new technique that alters protein production in mitochondria could help researchers understand mitochondrial diseases as ...

A team of researchers has uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron distribution. Disruption of this process was found to ...