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In the United States, more than 11% of men under the age of 49 are infertile. While the causes are varied and range from infections to hormonal imbalances, deformities during meiosis - a specialized ...

A genetic mutation in mice affects cells required for sexual reproduction and holds clues about male infertility that could ...

In the United States, more than 11% of men under the age of 49 are infertile. While the causes are varied and range from ...

They are formed in a woman's body before birth and have to be on standby for decades to possibly be fertilized one day. But as they age, they accumulate more and more DNA damage. Until now, it has ...

Meiosis is the generation of germ cells (eggs and sperm). In meiosis, DNA replication is followed by two division cycles: meiosis I, which segregates homologous chromosomes and meiosis II ...

Tight control over the location and timing of DNA cleavage in meiosis has further benefits beyond limiting DNA damage — for example, increasing control over subsequent steps in meiotic ...

used cutting-edge histochemical and transcriptomic methods to compare the responses of heat-tolerant and heat-sensitive wheat cultivars to heat stress during male meiosis. Their study revealed pivotal ...

During meiosis, crossover recombination is essential to link homologous chromosomes and drive faithful chromosome segregation. Crossover recombination is non-random across the genome, and ...

Inside the nucleus of a cell, the DNA is wound around histone proteins. This forms a structure called chromatin that allows the long DNA strands to fit inside the cell. Variations in chromatin ...