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Can a small fish help identify possible treatments for an ultra-rare inherited disease found in an Alabama boy? The genetic disease is XMEA, which progressively weakens the muscles and can affect the ...

Can a small fish help identify possible treatments for an ultra-rare inherited disease found in an Alabama boy? The genetic ...

Feng Wei at the Institute of Biophysics, Chinese Academy of Sciences, has made significant strides in understanding the BORC complex, a key player in lysosome transport and localization.

Lysosomes may also fuse with phagosomes and autophagosomes. Some phagocytosed pathogens can prevent or delay phagolysosome biogenesis; others escape their intracellular vacuole by degrading the ...

This also ensures that more vacuoles are present than the number of lysosomes which can digest them. In the study published in Microbes and Infection, the IISc team deduced that a critical protein ...

Scientists have pinpointed a protein in lysosomes that is involved in recycling a crucial fatty component of cell membranes to keep cells healthy. Researchers at Duke-NUS Medical School and ...

Long recognized as the cell’s recycling depot, a new study has found lysosomes act as signaling hubs that coordinate metabolism and longevity by communicating signals across tissues. According ...

In both cases, as the bacteria is drawn in, the cell membrane that surrounds it pinches off to form an intra-cellular compartment called the vacuole. For centuries, the various systems of ...

Here, we describe recent findings on the mechanisms underlying the formation and function of MCS between LDs and mitochondria, ER and lysosomes/vacuoles and the role of the cytoskeleton in promoting ...