Acute pancreatitis is among the most common gastrointestinal conditions requiring inpatient hospital care in the United ...

Cancer plasticity allows tumor cells to change their identity, evade therapies, and adapt to environmental pressures, contributing to treatment resistance and metastasis. New research is targeting ...

Lung cancer remains the world’s deadliest cancer, and cigarette smoke is its chief culprit. Chemicals in tobacco, such as ...

In this study, we investigated the interplay between cigarette smoke, DNA damage and repair, focusing on the Nucleotide Excision Repair (NER) protein ...

After decades of hype and setbacks, scientists have made impressive progress into tricking stem cells into repairing organs.

Dendritic cells (DC) are thought to be crucial in regulating (allo)immune airway damage and interactions with epithelial cells are likely. Studies in human lung transplantation are limited, however, ...

aInstitute of Digestive Disease and Department of Medicine and Therapeutics, State Key laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The ...

The human Lung Alveolus Chip is a 2-channel microfluidic culture system in which primary human lung alveolar epithelial cells are cultured in one channel where they are exposed to air as they ...

2011; Rock and Konigshoff, 2012; Baarsma et al., 2017). Adequate lung epithelial repair requires interactive cross-talk within the alveolar stem cell/progenitor niche between progenitor cells and ...

However, cell-free Deoxyribonucleic acid (cfDNA) originating from the lungs in the blood can be reported using DNA methylation patterns unique to the lung epithelium. Researchers used whole-genome ...

To get a better understanding of these differences on a cellular level, the team took lung tissue samples from healthy human donors and analyzed the genes within individual cells, which revealed ...

A team of researchers from the Netherlands, Germany and the U.S. reports that two drugs show promise in rejuvenating lung epithelial progenitor cells damaged by chronic obstructive pulmonary ...