Human lung microvascular endothelial cells (HL-mECs) were purchased from Lonza (Basel, Switzerland) and cultured in EGM-2 (Lonza), containing 10% FBS. Infections were carried out as previously ...

spectrumhealth.org The pulmonary endothelium is a dynamic, metabolically active layer of squamous endothelial cells ideally placed to mediate key processes involved in lung homoeostasis. Many of these ...

All 3 SLOs are highly organized structures with segregated B-cell and T-cell zones to optimize the induction of adaptive immune responses. GC indicates germinal centers; and HEV, high endothelial ...

There is a common misconception among many young people (under 50), particularly those who are not overweight and who exercise regularly, that they are fit and healthy. Many people in their 40s become ...

During development, the lymphatic vasculature forms as a second network derived chiefly from blood vessels. The transdifferentiation of embryonic venous endothelial cells (VECs) into lymphatic ...

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For over a decade, scientists have been growing organoids—small clusters of cells that mimic a particular organ—to serve as miniature biological models. Organoids of the brain have been used to study ...

As endothelial cells die after ischaemic injury ... obstruction mediated by red blood cells was least prominent in the lungs, despite this organ system being one of the most affected in people ...

Researchers identified compounds that expand the number of the healthy stem cells in the lungs, heart, joints, and eyes. (The concept of using small molecules this way is based on an earlier ...

Diverse subsets of endothelial progenitor cells (EPCs) are used for the treatment of ischemic diseases in clinical trials, and circulating EPCs levels are considered as biomarkers for coronary and ...

received accelerated approval for the treatment of patients with previously treated small-cell lung cancer. Whether tarlatamab is more effective than chemotherapy in the treatment of patients ...

Central to this process are oxidative stress, endothelial cell activation, inflammation, and vascular dysfunction. The endothelium exhibits a pro-inflammatory, pro-coagulant, and enhanced permeability ...