These studies highlight the inter-relationship between two classes of non-coding RNAs, miRNAs and lncRNAs, and epigenetic regulation of gene expression. They extend the known roles of miRNA such ...

Sequence for human HOTTIP RNA has been deposited with GenBank under the accession number GU724873. Microarray data are deposited in Gene Expression Omnibus (GEO) under accession number GSE26540.

In higher eukaryotes, a vast variety of RNAs is transcribed from genomic DNAs. The transcribed RNAs are subjected to RNA processing steps, such as splicing, ...

The startup’s first prospect is a heart medicine that works differently than the hypertrophic cardiomyopathy drugs developed ...

Non-coding RNAs (ncRNAs) are RNA molecules that do not encode proteins but are involved in dynamic cellular regulatory ...

Non-coding RNA ... represent small RNA molecules encoded in the genomes of plants and animals. These highly conserved 22 nucleotides long RNA sequences regulate the expression of genes by binding ...

Diederichs pooled the RNA samples from each group and analyzed the differences in gene ... that inhibit expression of tumor and metastasis suppressor genes, among others. HOTAIR has so far been linked ...

The tiny strings of RNA promote translation of a protein implicated in cancer, a hint they could regulate gene expression in more ways than previously thought ... neuroscience, and the natural world.

But researchers have long suspected ... precise exploration of RNA-based gene regulation and could one day help scientists better understand and even control gene expression in diseases.