These studies highlight the inter-relationship between two classes of non-coding RNAs, miRNAs and lncRNAs, and epigenetic regulation of gene expression. They extend the known roles of miRNA such ...

Sequence for human HOTTIP RNA has been deposited with GenBank under the accession number GU724873. Microarray data are deposited in Gene Expression Omnibus (GEO) under accession number GSE26540.

In higher eukaryotes, a vast variety of RNAs is transcribed from genomic DNAs. The transcribed RNAs are subjected to RNA processing steps, such as splicing, ...

Northwestern Medicine investigators have discovered that a novel long noncoding RNA (lncRNA), which are usually 200 ...

The startup’s first prospect is a heart medicine that works differently than the hypertrophic cardiomyopathy drugs developed ...

Non-coding RNA ... represent small RNA molecules encoded in the genomes of plants and animals. These highly conserved 22 nucleotides long RNA sequences regulate the expression of genes by binding ...

Diederichs pooled the RNA samples from each group and analyzed the differences in gene expression between ... that it has to be something noncoding.” The scientific community was resistant to the idea ...

Researchers have now mapped lncRNA (long non-coding RNA molecules ... controlled by so-called regulatory RNA molecules, i.e. RNA molecules that regulate gene activity and include both lncRNAs ...

The molecular pathways involved in antiviral defenses and counter-defenses in host-pathogen systems remain unclear. Researchers have used Neurospora crassa as a model organism to explore how RNA ...

But researchers have long suspected ... precise exploration of RNA-based gene regulation and could one day help scientists better understand and even control gene expression in diseases.