In higher eukaryotes, a vast variety of RNAs is transcribed from genomic DNAs. The transcribed RNAs are subjected to RNA processing steps, such as splicing, ...

Epigenetic modifications include methylation, histone modifications, and non-coding RNAs disturbances (59). Oncogene promoters can be demethylated and subsequently gene expression is elevated ...

Non-coding RNAs (ncRNAs) are RNA molecules that do not encode proteins but are involved in dynamic cellular regulatory ...

The startup’s first prospect is a heart medicine that works differently than the hypertrophic cardiomyopathy drugs developed ...

A research team from Sun Yat-sen University Sixth Affiliated Hospital has made a groundbreaking discovery in colorectal cancer (CRC) research, identifying a long noncoding RNA (lncRNA) named ...

Exosome non-coding ... Results RNA sequencing identified 182 candidate biomarkers for GC, of which 31 were validated as potential biomarkers by qRT-PCR. The combined diagnostic score (cd-score), ...

But researchers have long suspected ... precise exploration of RNA-based gene regulation and could one day help scientists better understand and even control gene expression in diseases.

It is the first big biopharma group to tap into Haya's platform, which identifies genes coding for long non-coding RNA ... which often involve control of gene expression and the regulation ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...