Correlation of drug-induced and drug-related ultra-high performance liquid chromatography-mass spectrometry serum metabolomic profiles yields discovery of effective constituents of Sini decoction ...

Dabigatran etexilate is a pro-drug, undergoing rapid ester hydrolysis to its active moiety, dabigatran, with no significant CYP 450 metabolism. 1,115 After oral administration, plasma concentrations ...