Introduction High dietary saturated fat intake is associated with higher blood concentrations ... may have different metabolic effects but trials have reported inconsistent results. We aimed to ...

Formation of RNA lipid nanoparticles by self-assembly begins when RNA in buffer is mixed with lipids in ethanol, and electrostatic interactions occur between RNA and cationic lipids in the core of ...

One method for delivering the mRNA to cells is by packaging it inside fatty spheres, called lipid nanoparticles, that protect it from being degraded. However, a common component of lipid ...

This fundamental study combines in vitro reconstitution experiments and molecular dynamics simulations to elucidate how membrane lipids are transported from the outer to the inner membrane of ...

In this study, researchers identified a lipid enzyme that maintains the expression level of thermal receptors and modulates cool temperature sensation and avoidance behavior. Thermal receptors ...

The findings have been published in Communications Chemistry. Lipid nanoparticles (LNPs) came to prominence for the delivery of RNA with the success of the Moderna and Pfizer BioNTech COVID-19 ...

Dietary fiber is essential for digestive, cardiovascular, and metabolic health, but most people fall short of daily ...

A study found that adding tiny natural messengers from cow reproductive fluids to lab-grown egg cells boosts maturation, ...

Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, United States ...