Credit: Technology Networks. Are DNA transformation and plasmid transformation the same? DNA transformation and plasmid transformation are the same thing: the uptake of genetic material from the ...

Three main mechanisms of HGT have been described: natural transformation ... applies more to integration of circular DNA than linear fragments. Most of the understanding of the processes ...

The manuscript, "A Linear DNA Vaccine Candidate Encoding the SARS-CoV-2 Receptor Binding Domain Elicits Protective Immunity in Domestic Cats," is available in preprint on bioRxiv and will be ...

Per the JDA, LineaRx and Takis/Evvivax will jointly develop linear DNA expression amplicons for TK7 and ConTRT, two of Takis/Evvivax’s anti-cancer vaccine candidates, utilizing LineaRx’s ...

Since uncontrolled disassembly of replication machineries causes genomic instability that may result in cellular transformation ... ring and loads it onto linear DNA molecule before DNA synthesis.

To summarize, the intramuscular delivery of the novel linear DNA SARS-CoV-2 vaccine aided by electroporation was determined to be safe and elicited humoral and cellular immune responses.

This revolutionary technology represents a significant advancement in synthetic DNA manufacturing, offering a cell-free, enzymatic process to generate linear DNA (linDNA) templates for in vitro ...

Under the terms of the Agreement, LineaRx and Takis/Evvivax will jointly develop linear DNA expression vectors for two of Takis/Evvivax's anti-cancer vaccine candidates utilizing LineaRx's linear ...