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Summary: A revolutionary microscopy method called LICONN enables scientists to reconstruct brain tissue and map synaptic connections using standard light microscopes. By embedding brain tissue in ...

Scientists have found a way to map the intricate patterns of cells in mouse brain tissue with an off-the-shelf light microscope, using a trick that inflates a tiny sample to 16 times its original ...

Because the approach described in this paper does not require any microscope or software modifications, it can be readily adopted by neuroscientists who wish to image neuronal activity deep in the ...