Typical patterns of involvement (T2-weighted magnetic resonance imaging [MRI]) in patients with adrenoleukodystrophy ... 66% of cases with abnormal brain MRIs who presented to our institute ...

Therefore, the choline signal can also be useful for distinguishing chronic from actively demyelinating lesions in adrenoleukodystrophy or adrenomyeloneuropathy (or other leukodystrophies), which ...

Leukodystrophy isn’t just one disease; it’s actually a group of diseases that affect the central nervous system. Doctors are discovering new forms of leukodystrophy all the time, but experts ...

Leukodystrophy refers to a group of rare genetic disorders affecting the central nervous system (CNS). The CNS includes the brain and spinal cord. The outlook for people with these disorders is ...

At a median follow-up of 6 years after lentiviral gene therapy, most patients with early cerebral adrenoleukodystrophy and MRI abnormalities ... on MRI of the brain that were characteristic ...

It may not be discovered until your doctor orders an MRI test for another reason. The two types of brain tissues are white matter and grey matter. Your brain is about 40% grey matter and 60% white ...

More information: Michelle C do Rosario et al, Variants in the zinc transporter TMEM163 cause a hypomyelinating leukodystrophy, Brain (2022). DOI: 10.1093/brain/awac295 ...