With little cash, a multitude of debt and creditors ready to pounce, Li-Cycle Holdings Inc. has filed for Chapter 15 bankruptcy protection, but that doesn’t necessarily mean its paused Rochester Hub ...

HDAC8, a member of class I HDACs, plays a pivotal role in cell cycle regulation by deacetylating the cohesin subunit SMC3. While cyclins and CDKs are well-established cell cycle regulators, our ...

With so much at stake, nature keeps it tightly controlled in a process called the cell cycle that scientists thought they thoroughly understood. But now it turns out there was more to know. Scientists ...

The contribution of the cell cycle to cell fate decisions has been well established in numerous types of stem cells, including pluripotent stem cells. Cell cycle length is an integral component of ...

Abstract: The cell cycle is the main process that regulates cell growth and development. The shape and size of cells and organelles change dynamically during the cell cycle. In this paper, deep neural ...

One of the fundamental biological processes in life is the cell cycle leading from DNA replication to cell division. While it has been studied for decades and our knowledge has matured ...

Coordination of cell proliferation and migration is fundamental for life, and its dysregulation has catastrophic consequences, such as cancer. How cell cycle progression affects migration, and vice ...

Across eukaryotes, the increasing level of cyclin-dependent kinase (CDK) activity drives progression through the cell cycle. As most cells divide at specific sizes, information responding to the size ...

The regenerative capacity of the heart after myocardial infarction is limited. Our previous study showed that ectopic introduction of 4 cell cycle factors (4F; CDK1 [cyclin-dependent kinase 1], CDK4 ...

Under normal physiological conditions, most of the renal cells are post-mitotic quiescent cells arrested in the G0 phase of cell cycle and renal cells turnover is very low. Injuries induced by toxins, ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The cell cycle is among the most basic ...