Adding genetic testing to clinical familial hypercholesterolemia screening improves risk assessment, prognosis and helps to guide targeted therapy.

When the amount of cholesterol in the blood is too high, hypercholesterolemia can develop, causing serious damage to the ...

Innovent Biologics, Inc. ("Innovent") (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures, and commercializes high-quality medicines for the treatment of oncology, ...

Study: Structure of apolipoprotein B100 bound to the low-density lipoprotein receptor. Image Credit: Nemes Laszlo / Shutterstock. In a recent study published in the journal Nature, researchers ...

A novel agent demonstrated a dose-dependent relationship with lectin-like oxidized LDL receptor-1 suppression, a mechanism to lower inflammatory and lipid risk, and was well tolerated in a small ...

PCSK9 prevents the LDL receptor from being recycled back to the cell surface. “The LDL receptors bind to LDL cholesterol and usher cholesterol out of the blood circulation,” Dr. Hsue explains.

Repatha (evolocumab) is a medicine that lowers “bad” cholesterol, also known as LDL (low-density lipoprotein).Repatha was FDA-approved in 2015. It is used in adults with heart disease to ...

When estrogen levels drop during menopause, these receptors don’t work as well, allowing more LDL (bad cholesterol) to remain in the bloodstream, explains Dr. Klodas.