In this study, we focused on apicoplastlocalized isocitrate dehydrogenase 1 (ICDH1) and deleted it using CRISPR-Cas9 technology. The ∆icdh1 mutant tachyzoites displayed markedly impaired growth ...

This image shows the five newly discovered superstructures. Quipu (red) is the largest structure found in the local universe. The others are Shapley (blue), Serpens-Corona Borealis (green ...

As a rate-limiting enzyme involved in the tricarboxylic acid cycle, the isocitrate dehydrogenase (IDH ... This article describes the basic structure of IDH1, the possible diseases caused by IDH1 ...

Edited by Perry Allen Frey, University of Wisconsin, Madison, WI, and approved June 7, 2017 (received for review May 2, 2017) ...

Figure 1: The overall structure of AceK. Figure 2: The ATP-binding site and the allosteric AMP-binding site in AceK. On the basis of the structural and mutagenesis studies, we rationalize the ...

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