First Canadian to receive procedure says she would do it ‘a million times over’ compared with previous work to keep blood ...

In islet cell transplantation, beta cells are removed from a donor's pancreas and transferred into a person with type 1 diabetes. Beta cells are one type of cell found in the islets of the ...

A single infusion of zimislecel, an investigational stem cell-based therapy, restored physiologic islet function and ...

Pancreatic islet transplantation is an effective β-cell replacement therapy that has the capacity to normalize glycaemic control in patients with type 1 diabetes mellitus To date, over 1,500 ...

One-year data suggest allogeneic stem cell-derived islet-cell therapy could become a future option for those with type 1 ...

Islets are cell groups within the pancreas which are comprised of beta cells – the cells that make insulin, the hormone that regulates blood glucose levels. Recent advances in medical science have ...

With respect to islet transplantation a further difficulty is that many of the current agents damage beta cells or induce peripheral insulin resistance. 4 To address this problem, we developed a ...

Most in a small group of patients receiving a stem cell-based infusion no longer needed insulin, but the drug may not suit those with more manageable type 1 diabetes.

Marlaina Goedel was diagnosed with Type 1 diabetes at age 5 and recently underwent an islet cell transplant. Courtesy Marlaina Goedel via UChicago Medicine Goedel said her diabetes became so ...

In the United States, where islet-cell transplants are still considered experimental, Vertex Pharmaceuticals of South Boston, Massachusetts, is actively involved in U.S. research and clinical trials.