Chronic inflammation increases NETs formation, which remodels the extracellular matrix (ECM) due to the presence of proteases such as MMP-9 or proteinase 3 (PR3). The degraded ECM proteins, ...

Cancer cell movement during metastasis is a dynamic process regulated by several different signals. However, the way cells ...

A fluorescent resonance energy transfer receptor for visualizing invading cancer cell dynamics has been developed.

Most of the cells in our bodies don't move—they stay where they're supposed to in service to our organs and biological ...

Cancer cell movement during metastasis is a dynamic process regulated by several different signals. However, the way cells ...

Methods: In this study, poly (caprolactone) (PCL) nanofibers, PCL nanofibers uniformly coated with the extracellular matrix derived from endothelial cells (ECd), and bi-directional linear gradient ECd ...

In this manuscript, the authors have taken a useful first step towards better understanding this protein using a loss of function model in trophoblast cell lines and then examining invasion, ...

Find more information on the Altmetric Attention Score and how the score is calculated. The extracellular matrix (ECM) is a critical non-cellular component of multicellular organisms containing a ...

Consideration of how the extracellular matrix directs cell behavior will be crucial to the success of regenerative therapies. Context-specific mechanical deformation of particular substrates ...

In in vivo conditions, cells directly interact with their surrounding microenvironment, the extracellular matrix, which is secreted by cells and composed of a complex mixture of polysaccharides and ...

Sternocutaneous fistulas are extremely rare, and the only definite therapy is surgical repair. Our experience taught us that combining a traditional approach with an extracellular matrix patch might ...