This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...

The ability to persist inside macrophages means that these bacteria can evade both antibiotics and the body’s natural defences.” The breakthrough could lead to new treatment strategies that target ...

P. I. Fields, R. V. Swanson, C. G. Haidaris, F. Heffron, Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent. Proc. Natl. Acad ...

Single molecule dynamics reports on the molecular interactions in real-time, acting as a probe for changes in the intracellular environment ... mesophilic and psychrophilic bacteria. In addition to ...

This enables the nanostructure to recognize and accumulate in cancerous tissue. To achieve intracellular activation, the researchers attached two hairpin-shaped DNA strands at other vertices. These ...

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acssynbio.4c00612. Time-lapse video of cells with LAA-LAA-Osc in a ...

Department of Chemistry and Centre for Synthetic Biology, Technical University of Darmstadt, Peter-Grünberg-Str. 4, 64287 Darmstadt, Germany Department of Pure and Applied Chemistry, University of ...

The immune system is a complex network of various cellular components that must differentiate between pathogenic bacteria and the commensal bacteria of the human microbiome ... and washed 2 × 100 μl ...

The hydrothermal vent tubeworm Riftia pachyptila hosts a single 16S rRNA phylotype of intracellular sulfur-oxidizing symbionts ... see Appendix section B. Proteins involved in the bacterial cell cycle ...

When a bacterium enters a cell’s cytoplasm, intracellular lipid droplets close in, bringing with them an arsenal of antimicrobial proteins, the research shows. “This is the first evidence that there’s ...