Finally, it is still unclear whether GVIN coatomers restrict bacterial cell-to-cell spread and if they can effectively contain infections in animal models. In summary, this study highlights the immune ...

† Department of Chemistry, Infection Innovative Medicines Unit, AstraZeneca-US, 53 Gatehouse Drive, Waltham, Massachusetts 02451, United States ‡ Department of Biosciences, Infection Innovative ...

Innovation Research Center for AIE Pharmaceutical Biology, Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of ...

Current tools for optogenetic control of intracellular calcium signals currently suffer from slow response time or low dynamic range. Here the authors develop blue light-activated Ca2+ channel ...

Royalty-free licenses let you pay once to use copyrighted images and video clips in personal and commercial projects on an ongoing basis without requiring additional payments each time you use that ...

Cellular immunity is most effective against cells infected with viruses, intracellular bacteria, fungi and protozoans, and cancerous cells. It also mediates transplant rejection. Mucosal vaccines ...

Background: The colonic epithelium maintains a life long reciprocally beneficial ... Cell associated enteropathogens were defined as adherent plus intracellular bacteria and quantified by CFU counts ...

While hypolipidemia characterizes VL, LD, a cholesterol auxotroph, relies on host lipid scavenging for its intracellular survival. The aggressive pathology, in terms of increased organ parasite load, ...