In this experiment, we examined the mechanisms for Ang II-induced activation of IL-6 gene expression in cultured rat VSMCs ... Both IκB proteolysis and p105 processing are mediated by the ...

We are very confident that tocilizumab (a medicine that blocks interleukin‐6 (IL-6)) reduces the number of hospitalized people who die from COVID-19 within 28 days of treatment. However, it probably ...

An anti-inflammatory diet can counteract chronic low-grade inflammation by modulating immune responses, gut health, and key ...

Fermented foods have been a cornerstone of human diets for millennia, offering preservation and health benefits. Long before ...

In active SLE, CRP levels are disproportionally low for increased IL-6 levels. While a molecular explanation is lacking, these low CRP levels have been found associated with increased type I ...

As strange as this may sound, scientists believe that at least one type of bacteria in your gut actually causes depression, ...

Carbon monoxide mediated these anti-inflammatory effects not through a guanylyl cyclase–cGMP or nitric oxide pathway ... of IL-10 (data not shown). Figure 6: Effect of CO on LPS-induced TNF ...

Renal failure in multiple myeloma typically occurs when the kidneys fail to filter waste products from the blood, leading to ...

Researchers have found a genetic link between the nighttime production of the sleep hormone melatonin and ADHD symptom ...

A large study in the Netherlands has found that inflammation is consistently linked to symptoms of depression and anxiety, as ...

Here we identify the interleukin (IL)-33 and its receptor ST2 as key negative regulators of wound ... Wild-type and St2 −/− mice were used in wound healing experiments and in two experimental models ...

While the immunomodulatory pathways initiated in immune cells contribute to therapeutic response, their activation in cancer cells play a role in cancer progression. Also, many of the aberrantly ...