T-cell-based immunotherapies have transformed the treatment, offering cures to subsets of cancer patients. The rate-limiting step in developing safe and effective new immunotherapies is the ...

Sun Yat-sen University, Guangzhou, China.

Cancer vaccines have been a tantalizing idea for decades, but the vast complexity of the human immune system has posed significant challenges. Now, technological advances like rapid DNA sequencing ...

uGDB, utilizing next-generation sequencing to detect bladder cancer-associated mutations and DNA alterations, has previously shown associations with recurrence and therapy response.

APC, Antigen Presenting Cells, which could be Neutrophils, Dendritic cells, or monocytes/macrophages. Figure prepared using BioRender. Increased tumor infiltration of neutrophils, often accompanied by ...

Chemotherapy regimens chosen by the ChemoID assay dramatically increased ORR in patients with platinum-resistant ovarian cancer. A chemotherapeutic assay (ChemoID) designed to to select targeted ...

The incidence of prostate cancer is increasing. Screening with an assay of prostate-specific antigen (PSA) has a high rate for false positive results. Genomewide association studies have ...

genome.med.kyoto-u.ac.jp Background Prostate-specific antigen (PSA) is a useful marker for prostate cancer (PCa) and is widely used for screening of PCa ... PSA levels were quantified by ...

Whole-cell tumor vaccines are advantageous because of their ability to induce a broad and multifaceted immune response through the presentation of a wide range of tumor antigens, thereby enhancing the ...

It is well known that men are reluctant to see a doctor, especially a urologist. As a result, there is a risk that prostate ...