Researchers at The Wistar Institute have identified a previously unknown mechanism by which viruses can reprogram mitochondrial structure to silence immune responses and ensure successful viral ...

including innate immune responses to viruses and bacteria, the development and activation of lymphocytes, and the maintenance of immunological tolerance. The substrate binding of some DUBs ...

Researchers have tracked how the COVID-19 virus mutates long term, revealing patterns that could help predict the emergence ...

They are "seeing" the physical, atomic structure of two protein structures ... necessary for proper development and immune regulation. They also know it becomes dysregulated in the immune systems ...

the virus is never eliminated from the body, as it integrates into the genome of infected host cells and has several immune evasion strategies. These include antigenic variability, the structure ...

A breakdown of how memory B, T, and innate cells remember past infections and how this insight powers vaccines and immunotherapies.

Hepatitis B virus-induced hepatocellular carcinoma (HCC) remains a major global health burden, and new therapeutic and ...

A new type of mRNA vaccine is more scalable and adaptable to continuously evolving viruses such as SARS-CoV-2 and H5N1, according to a study by researchers at University of Pittsburgh School of Public ...

However, the ongoing evolution of the virus regularly produces new variants ... One of the fundamental mechanisms in immune defense is the formation of antibodies that can recognize pathogens ...

LINE-1, a "jumping gene" making up 20% of the genome, invades DNA during cell division using protein-RNA clusters, offering ...

Over the last 10 years, breakthroughs in understanding the genetic instructions passed from parent to offspring have put ...