Exploration of the effects of this pathway is underway. An effort to clarify the role of IL-33/ST2 in the crosstalk between end-organ effector cells and their environment, specifically the ...

Interleukin (IL)-23 is a validated therapeutic target in inflammatory bowel disease ... Oral administration of this VHH achieves deep pathway inhibition in a murine colitis model. Furthermore, a ...

This month's cover highlights the article EGFR controls transcriptional and metabolic rewiring in KRASG12D colorectal cancer by Dana Krauß, Maria Sibilia and colleagues. The tumor-intrinsic role of ...

Zai Lab Limited (NASDAQ: ZLAB; HKEX: 9688) today announced new data from its preclinical study of ZL-1503, the Company’s ...

Creative Biolabs recently updated its antibody chip platform, expanding product arrays for phosphorylation signaling and cytokine detection. SHIRLEY, NY, UNITED STATES, May 27, 2025 /EINPresswire.com/ ...

The Interleukin-12 (IL-12) family ligand subunits (IL-12s) and receptor subunits (IL-12Rs) constitute pivotal regulators of immune homeostasis, with direct implications in autoimmune pathologies and ...

IL-12 is a powerful cytokine, a type of protein that acts as a chemical messenger, that plays a key role in initiating the body’s natural immune response. Several studies of IL-12 ...

The Wnt/ß-catenin signaling is a highly conserved pathway that orchestrates several biological functions ... Typically, Research Topics are online and open for submissions within a few weeks and ...

Inflammatory mediators like cytokines and chemokines play a key role in driving age-related and postmenopausal breast cancer progression and immune system changes.

As strange as this may sound, scientists believe that at least one type of bacteria in your gut actually causes depression, ...

Dupilumab was approved by the FDA to treat bullous pemphigoid, that demonstrated its efficacy in achieving sustained disease ...