Here, we investigated the effects of the P2X7R inhibitor AFC-5128, a CNS-penetrating small molecule, in an established animal model of chronic MS, experimental autoimmune encephalomyelitis (EAE). Our ...

Cite this: Functional Interleukin-17 Receptor A is Expressed in Central Nervous System Glia and Upregulated in Experimental Autoimmune Encephalomyelitis - Medscape - Apr 01, 2009. 1 Department of ...

1 Diseases Associated with Aging and Regeneration, Biomedical Research, Novartis Pharma AG, Basel, Switzerland 2 Immunology Disease Area, Biomedical Research, Novartis Pharma AG, Basel, Switzerland ...

This review highlights the key areas of research in the hypothalamic control of appetite. The hypothalamus consists of several nuclei that integrate peripheral signals, such as adiposity and ...

126.com Aims To investigate the effect of succinic acid on the development of experimental autoimmune uveitis (EAU) and the underlying mechanism. Methods Succinic acid was administrated ...

163.com Aims To evaluate the safety and efficacy of intravitreal injection of liposomes encapsulating infliximab in experimental autoimmune uveoretinitis (EAU) rats. Methods Liposomes containing ...

The latest start-up to emerge from the Roivant stable is named Priovant Therapeutics, and has been formed to develop a JAK1/TYK2 inhibitor originated by Pfizer as a treatment for autoimmune diseases.

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This case illustrates a 13-year-old boy presented with short history of intellectual decline, headache, papilloedema, cranial nerve palsy, myoclonus with suggestive neuroimaging mimicking acute ...

The new estimate suggests that approximately 404,000 people are affected by ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome), a 62% rise from the previously accepted figure of 250,000.