SAN DIEGO -- Treatment with hydroxyurea led to more hematologic dose-limiting toxicities (DLTs) compared with placebo in patients with hemoglobin SC, a milder form of sickle cell disease (SCD), a ...

Compared to drugs that simply ease the symptoms of sickle-cell disease, DMTs can slow disease progression by treating the root cause. For example, the chemo drug hydroxyurea, one of the most used ...

Crizanlizumab (Adakveo) failed to outperform placebo in patients with sickle cell disease, the phase III STAND trial showed.

Sickle-cell trait haplotype distribution shows the ... as patients may experience symptoms of differing severity and varied responses to hydroxyurea regardless of haplotype. So, although these ...

Children with sickle cell disease, a chronic hemolytic anemia ... As well as investigating the role of genes and the possibility that hydroxyurea or blood pressure control reduce neurological ...

Sickle cell is managed with, among other drugs, hydroxyurea which reduces its severity and complications. The drug is common in Africa where majority of patients are unable to afford bone marrow ...

Scientists from Johns Hopkins Medicine and eight other institutions in the United States, Africa and Europe say they have ...

Western, Nyanza and Coast counties residents are classified as being at high risk of developing sickle cell diseases. One tablet, for example, hydroxyurea, costs Sh50. The medication roughly costs ...

Feb. 25, 2025 — A bone marrow transplant process is safe and curative for adults with sickle cell disease, according to results of a trial completed at about 20 cancer ... Brains of People With ...