Get Instant Summarized Text (Gist) A machine learning model has identified a previously unknown hydrogenation mechanism for superhydride synthesis, revealing that surface melting of CaH 2 under ...

Most of the early studies on the BFDC reaction mechanism were focused on identifying the contributions of the ionizable active site residues to each of the individual steps in the mechanism (Sergienko ...

Cytochrome P450 17A1 (CYP17A1) catalyzes C17 hydroxylation of pregnenolone and progesterone and the subsequent C17–C20 bond cleavage (lyase reaction) to form androgen precursors. Compound I (Cpd I) ...

Insights into the reaction mechanism. ... B. G. Crystallographic and catalytic studies of the peroxide-shunt reaction in a diiron hydroxylase. Biochemistry 48, 8932–8939 (2009) ...

Therefore, we propose that the hydroxylase reaction is a general functionality of PPOs. ... evidenced hydroxylation activity of AUS1 toward its natural substrate in combination with the consistent ...

Catechol oxidases and tyrosinases belong to the family of polyphenol oxidases (PPOs). In contrast to tyrosinases, catechol oxidases were so far defined to lack hydroxylase activity toward monophenols.

Hypoxia creates prerequisites for inactivation of prolyl hydroxylase reactions and thereby provides HIF-1α stabilization and accumulation, induction of HIF-1α transcription and translocation to the ...

The properties of ascorbic acid and the mechanism of display of its oxidant and prooxidant properties are ... Aristova, N. , Burhina, O. and Soshnikova, O. (2012) Mechanism of chemiluminescence in ...