Using this multifunctionality, this work aims at presenting the development, fabrication, and validation of an SMA-driven robotic end-effector. The end-effector prototype is designed in a modular ...

To confirm that the repressive effect we observed with dCas9-G9a-SD is not caused by CRIPSRi, we included a “CRISPRi control” (dCas9 without effector) targeted to the same sequence 475 bp upstream of ...

Results: In this study, we show that LKB1 is essential for ILC3 postnatal development, effector function, and intestinal immunity. LKB1-deficient mice exhibit a marked decrease in ILC3 number at 2 -3 ...

Objective Gut homing of lymphocytes via adhesion molecules has recently emerged as new target for therapy in IBDs. We aimed to analyse the in vivo homing of effector (Teff) and regulatory (Treg) T ...

Contributed by Chi-Huey Wong, October 13, 2021 (sent for review August 11, 2021; reviewed by Xi Chen and Bruce R. Zetter) ...

This article reports the design, synthesis, and evaluation of a novel class of molecules of intermediate size (approximately 7000 Da), which possess both the targeting and effector functions of ...

The mechanism of memory induction and memory-driven effector function (trained immunity) in ILC2s is unknown. Objective: NFκB1 is preferentially expressed at a high level in ILC2s. We examined the ...