The mechanism of memory induction and memory-driven effector function (trained immunity) in ILC2s is unknown. Objective: NFκB1 is preferentially expressed at a high level in ILC2s. We examined the ...

Using this multifunctionality, this work aims at presenting the development, fabrication, and validation of an SMA-driven robotic end-effector. The end-effector prototype is designed in a modular ...

Correspondence to Dr Jian Zhang, Institute of Immunopharmaceutical Sciences, School of Pharmaceutical Sciences, Shandong University, Shandong, 250012, China; zhangj65{at}sdu.edu.cn Objective Chronic ...

Department of Host-Microbe Interactions, St. Jude Children’s Research Hospital, Memphis, Tennessee 38105, United States ...

This article reports the design, synthesis, and evaluation of a novel class of molecules of intermediate size (approximately 7000 Da), which possess both the targeting and effector functions of ...

Figure 1: Targeted disruption of the mouse C3aR gene. Figure 3: Assessment of AHR to inhaled methacholine (MCh) in conscious mice. We immunized mice with 10 µg of OA and 1 mg of aluminium ...

Objective Gut homing of lymphocytes via adhesion molecules has recently emerged as new target for therapy in IBDs. We aimed to analyse the in vivo homing of effector (Teff) and regulatory (Treg) T ...

Results: In this study, we show that LKB1 is essential for ILC3 postnatal development, effector function, and intestinal immunity. LKB1-deficient mice exhibit a marked decrease in ILC3 number at 2 -3 ...

However, it takes three to five days for sufficient numbers of clones to be produced and to differentiate into effector cells, which allows more than enough time for most pathogens to damage the host.

Contributed by Chi-Huey Wong, October 13, 2021 (sent for review August 11, 2021; reviewed by Xi Chen and Bruce R. Zetter) ...